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KPV peptide, a naturally occurring tripeptide made up of lysine, proline, and valine, exhibits anti-inflammatory characteristics. It has been used successfully in topical creams for skin conditions including as acne, eczema, and psoriasis, and it has showed promise in treating inflammatory bowel diseases such as ulcerative colitis and irritable bowel syndrome.
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This product is intended for research purposes only. To be used by trained professionals only.
The KPV pre mixed peptide, a naturally occurring tripeptide made up of lysine, proline, and valine, is attracting substantial attention in the scientific community due to its wide variety of possible medicinal applications. Notably, multiple research have emphasised its anti-inflammatory capabilities, which have implications for a number of health issues.
KPV peptides were found to increase intracellular calcium in human keratinocyte cells, a key mechanism for skin cell activity and regeneration [1]. This shows that KPV may be useful in the treatment of skin conditions such acne, eczema, and psoriasis. Another study in the found that KPV prevented the migration of polymorphonuclear leukocytes (PMNs) and the production of proinflammatory mediators in a urate peritonitis model [2].
KPV pre mixed peptide has showed promise in the treatment of inflammatory bowel disease in the field of gastroenterology. A piece of research found that the PepT1-mediated tripeptide KPV decreased intestinal inflammation [3], implying a potential involvement in the treatment of disorders such as ulcerative colitis and irritable bowel syndrome. Furthermore, the KPV pre mixed peptide has been investigated as a fluorescent probe target in imaging studies of chronic and acute ulcerative colitis [4].
The effect of KPV in tumorigenesis inhibition has also been studied. According to one trial, KPV pre mixed peptide may slow the growth of colitis-associated cancer [5]. Furthermore, antimicrobial peptide research revealed the potential therapeutic applications of a dimeric octamer peptide composed of two units of KPV peptide joined by a cysteine-cysteine linker [6].
[1] https://www.sciencedirect.com/ science/article/pii/S0022202X15 307697
[2] https://jpet.aspetjournals.org/ content/306/2/631.short
[3] https://www.sciencedirect.com/ science/article/abs/pii/S00165085 07018525
[4] https://pubs.acs.org/doi/abs/ 10.1021/acsami.7b00936
[5] https://www.sciencedirect.com/ science/article/pii/S2352345X16 000151
[6] https://www.mdpi.com/1420-3049/ 17/10/12276
Sequence: Lys-Pro-Val
Molecular Formula: C16H30N404
Molecular Weight: 342.43 g/mol
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our New Zealand Direct Peptides website: https://new-zealand.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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